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1

Alternatives to animal testing: current status and future perspectives

Manfred Liebsch, Barbara Grune, Andrea Seiler, Daniel Butzke, Michael Oelgeschläger, Ralph Pirow, Sarah Adler, Christian Riebeling, Andreas Luch

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 811 KB

english, 2011

2

How Far Is the Union Interested in the Continent of Africa?

Journal:

Journal of the Royal African Society

Year:

1937

Language:

english

File:

PDF, 407 KB

english, 1937

3

Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility

Reisinger, Kerstin, Blatz, Veronika, Brinkmann, Joep, Downs, Thomas R., Fischer, Anja, Henkler, Frank, Hoffmann, Sebastian, Krul, Cyrille, Liebsch, Manfred, Luch, Andreas, Pirow, Ralph, Reus, Astrid A

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2018

Language:

english

File:

PDF, 822 KB

english, 2018

4

Estrogen and Progestogen Correlates of the Structure of Female Copulation Calls in Semi-Free-Ranging Barbary Macaques (Macaca sylvanus)

Dana Pfefferle, Michael Heistermann, Ralph Pirow, J. Keith Hodges, Julia Fischer

Journal:

International Journal of Primatology

Year:

2011

Language:

english

File:

PDF, 251 KB

english, 2011

5

The EFSA assessment of the risks to public health associated with bisphenol A (BPA) exposure

Husøy, T., Hart, A., Pirow, R., Mennes, W.C., Wölfle, D., Fowler, P.A., Gundert-Remy, U., von Götz, N., Woutersen, R.A., Arcella, D., Theobald, A., Croera, C., Castoldi, A.F.

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 71 KB

english, 2015

6

Six Ages of Man as Determined by Athletic Performance

Journal:

The International Journal of Aging and Human Development

Year:

1994

Language:

english

File:

PDF, 1.84 MB

english, 1994

7

Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study

Bekker, Pirow, Dairaghi, Daniel, Seitz, Lisa, Leleti, Manmohan, Wang, Yu, Ertl, Linda, Baumgart, Trageen, Shugarts, Sarah, Lohr, Lisa, Dang, Ton, Miao, Shichang, Zeng, Yibin, Fan, Pingchen, Zhang, Pen

Journal:

Year:

2016

Language:

english

File:

PDF, 2.96 MB

english, 2016

8

Non-invasive estimation of domestic hot water usage with temperature and vibration sensors

Pirow, N.O., Louw, T.M., Booysen, M.J.

Journal:

Flow Measurement and Instrumentation

Year:

2018

Language:

english

File:

PDF, 635 KB

english, 2018

9

Correction: Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study

Bekker, Pirow, Dairaghi, Daniel, Seitz, Lisa, Leleti, Manmohan, Wang, Yu, Ertl, Linda, Baumgart, Trageen, Shugarts, Sarah, Lohr, Lisa, Dang, Ton, Miao, Shichang, Zeng, Yibin, Fan, Pingchen, Zhang, Pen

Journal:

Year:

2019

Language:

english

File:

PDF, 1.40 MB

english, 2019

10

Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate

Mark C. Genovese, Stanley Cohen, Larry Moreland, Deborah Lium, Sean Robbins, Richard Newmark, Pirow Bekker, for the 20000223 Study Group

Journal:

Arthritis & Rheumatism

Year:

2004

Language:

english

File:

PDF, 109 KB

english, 2004

11

Acetone to MIBK process optimization through multidisciplinary chemometrics and in-line NIR spectroscopy

Nicolaas M. Prinsloo, J. Pirow Engelbrecht, Thomas N. Mashapa, Margaret J. Strauss

Journal:

Applied Catalysis A: General

Year:

2008

Language:

english

File:

PDF, 591 KB

english, 2008

12

Thermal acclimation in the microcrustacean Daphnia: a survey of behavioural, physiological and biochemical mechanisms

R.J. Paul, T. Lamkemeyer, J. Maurer, O. Pinkhaus, R. Pirow, M. Seidl, B. Zeis

Journal:

Journal of Thermal Biology

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

13

Acclimation of the microcrustacean Daphnia magna to warm temperatures is dependent on haemoglobin expression

M.D. Seidl, R. Pirow, R.J. Paul

Journal:

Journal of Thermal Biology

Year:

2005

Language:

english

File:

PDF, 483 KB

english, 2005

14

A pharmaco-scintigraphy study of riboflavin 5′-phosphate sodium capsules (1 vs. 4)

Raymond N Dansereau, Richard J Dansereau, Bruce R Line, Daniel Healy, Pirow Bekker

Journal:

International Journal of Pharmaceutics

Year:

1997

Language:

english

File:

PDF, 413 KB

english, 1997

15

Acclimatory responses of theDaphnia pulexproteome to environmental changes. II. Chronic exposure to different temperatures (10 and 20°C) mainly affects protein metabolism

Susanne Schwerin, Bettina Zeis, Tobias Lamkemeyer, Rüdiger J Paul, Marita Koch, Johannes Madlung, Claudia Fladerer, Ralph Pirow

Journal:

Year:

2009

Language:

english

File:

PDF, 2.29 MB

english, 2009

16

Physiological responses ofDaphnia pulexto acid stress

Anna K Weber, Ralph Pirow

Journal:

Year:

2009

Language:

english

File:

PDF, 1.56 MB

english, 2009

17

Acclimatory responses of theDaphnia pulexproteome to environmental changes. I. Chronic exposure to hypoxia affects the oxygen transport system and carbohydrate metabolism

Bettina Zeis, Tobias Lamkemeyer, Rüdiger J Paul, Frank Nunes, Susanne Schwerin, Marita Koch, Wolfgang Schütz, Johannes Madlung, Claudia Fladerer, Ralph Pirow

Journal:

Year:

2009

Language:

english

File:

PDF, 1.54 MB

english, 2009

18

Epipodite and fat cells as sites of hemoglobin synthesis in the branchiopod crustaceanDaphnia magna

Torsten Goldmann, Bertram Becher, Klaus H. Wiedorn, Ralph Pirow, Michael E. Deutschbein, Ekkehard Vollmer, Rüdiger J. Paul

Journal:

Histochemistry and Cell Biology

Year:

1999

Language:

english

File:

PDF, 322 KB

english, 1999

19

Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?

Andrea Seiler, Michael Oelgeschläger, Manfred Liebsch, Ralph Pirow, Christian Riebeling, Tewes Tralau, Andreas Luch

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 2.14 MB

english, 2011

20

Circulatory oxygen transport in the water fleaDaphnia magna

C. Bäumer, R. Pirow, R. Paul

Journal:

Journal of Comparative Physiology B

Year:

2002

Language:

english

File:

PDF, 294 KB

english, 2002

21

Cationic composition and acid–base state of the extracellular fluid, and specific buffer value of hemoglobin from the branchiopod crustaceanTriops cancriformis

Ralph Pirow, Ina Buchen, Marc Richter, Carsten Allmer, Frank Nunes, Andreas Günsel, Wiebke Heikens, Tobias Lamkemeyer, Björn M. von Reumont, Stefan K. Hetz

Journal:

Journal of Comparative Physiology B

Year:

2009

Language:

english

File:

PDF, 629 KB

english, 2009

22

Population PK–PD model for Fc-osteoprotegerin in healthy postmenopausal women

Matthew L. Zierhut, Marc R. Gastonguay, Steven W. Martin, Paolo Vicini, Pirow J. Bekker, Donna Holloway, Philip T. Leese, Mark C. Peterson

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2008

Language:

english

File:

PDF, 848 KB

english, 2008

23

Control of oxygen transport in the microcrustacean Daphnia: regulation of haemoglobin expression as central mechanism of adaptation to different oxygen and temperature conditions

R. J. Paul, B. Zeis, T. Lamkemeyer, M. Seidl, R. Pirow

Journal:

Acta Physiologica

Year:

2004

Language:

english

File:

PDF, 393 KB

english, 2004

24

Temporal environmental change, clonal physiology and the genetic structure of a Daphnia assemblage (D. galeata–hyalina hybrid species complex)

OLAF PINKHAUS, SUSANNE SCHWERIN, RALPH PIROW, BETTINA ZEIS, INA BUCHEN, ULRIKE GIGENGACK, MARITA KOCH, WOLFGANG HORN, RÜDIGER J. PAUL

Journal:

Freshwater Biology

Year:

2007

Language:

english

File:

PDF, 450 KB

english, 2007

25

Post-Conflict Affiliation in Barbary Macaques is Influenced by Conflict Characteristics and Relationship Quality, but Does Not Diminish Short-Term Renewed Aggression

Annika Patzelt, Ralph Pirow, Julia Fischer

Journal:

Year:

2009

Language:

english

File:

PDF, 211 KB

english, 2009

26

Facial expressions modulate the ontogenetic trajectory of gaze-following among monkeys

Christoph Teufel, Anke Gutmann, Ralph Pirow, Julia Fischer

Journal:

Developmental Science

Year:

2010

Language:

english

File:

PDF, 626 KB

english, 2010

27

Native and subunit molecular mass and quarternary structure of the hemoglobin from the primitive branchiopod crustacean Triops cancriformis

Morgane Rousselot, Elmar Jaenicke, Tobias Lamkemeyer, J. Robin Harris, Ralph Pirow

Journal:

Year:

2006

Language:

english

File:

PDF, 1.70 MB

english, 2006

28

Oxygen binding and its allosteric control in hemoglobin of the primitive branchiopod crustacean Triops cancriformis

Ralph Pirow, Nadja Hellmann, Roy E. Weber

Journal:

Year:

2007

Language:

english

File:

PDF, 1.43 MB

english, 2007

29

A Single-Dose Placebo-Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women

Pirow J Bekker, Donna L Holloway, Amy S Rasmussen, Robyn Murphy, Steven W Martin, Philip T Leese, Gregory B Holmes, Colin R Dunstan, Alex M DePaoli

Journal:

Journal of Bone and Mineral Research

Year:

2004

Language:

english

File:

PDF, 99 KB

english, 2004

30

The Effect of a Single Dose of Osteoprotegerin in Postmenopausal Women

Pirow J. Bekker, Donna Holloway, Arline Nakanishi, Michael Arrighi, Philip T. Leese, Colin R. Dunstan

Journal:

Journal of Bone and Mineral Research

Year:

2001

Language:

english

File:

PDF, 305 KB

english, 2001

31

A Single-Dose Placebo-Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women

Pirow J Bekker, Donna L Holloway, Amy S Rasmussen, Robyn Murphy, Steven W Martin, Philip T Leese, Gregory B Holmes, Colin R Dunstan, Alex M DePaoli

Journal:

Journal of Bone and Mineral Research

Year:

2005

Language:

english

File:

PDF, 3.98 MB

english, 2005

32

Risedronate Gastrointestinal Absorption Is Independent of Site and Rate of Administration

David Y. Mitchell, Rachelle A. Eusebio, Lisa E. Dunlap, Karen A. Pallone, John D. Nesbitt, Darrell A. Russell, Marian E. Clay, Pirow J. Bekker

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 395 KB

1998

33

Water fleas (Daphnia magna) provide a separate ventilatory mechanism for their brood

Matthias D. Seidl, Ralph Pirow, Rüdiger J. Paul

Journal:

Year:

2002

Language:

english

File:

PDF, 1.44 MB

english, 2002

34

Arenicola marina extracellular hemoglobin: a new promising blood substitute

Morgane Rousselot, Eric Delpy, Christophe Drieu La Rochelle, Vincent Lagente, Ralph Pirow, Jean-François Rees, Agnès Hagege, Dominique Le Guen, Stéphane Hourdez, Franck Zal

Journal:

Biotechnology Journal

Year:

2006

Language:

english

File:

PDF, 568 KB

english, 2006

35

Risedronate in Paget's disease: Preliminary results of a multicenter study

Jacques P. Brown, Jelle W. Kylstra, Pirow J. Bekker, Douglas W. Axelrod, Ethel S. Siris, Roy D. Altman, Frederick R. Singer

Journal:

Seminars in Arthritis and Rheumatism

Year:

1994

Language:

english

File:

PDF, 90 KB

english, 1994

36

Acclimatory responses of the Daphnia pulex proteome to changes in oxygen and temperature conditions

B. Zeis, S. Schwerin, R. Pirow, T. Lamkemeyer, R.J. Paul

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2008

Language:

english

File:

PDF, 60 KB

english, 2008

37

Optical measurement of oxygen and metabolism in hypoxic invertebrates

R.J. Paul, R. Pirow

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2000

Language:

english

File:

PDF, 109 KB

english, 2000

38

Development of heart rate responses to acoustic stimuli in Muscovy duck embryos

Joachim Höchel, Ralph Pirow, Martin Nichelmann

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2002

Language:

english

File:

PDF, 1.08 MB

english, 2002

39

Systemic and metabolic responses in Daphnia magna to anoxia

Rüdiger J. Paul, Michael Colmorgen, Ralph Pirow, Yi-Horn Chen, Ming-Cheng Tsai

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1998

Language:

english

File:

PDF, 690 KB

english, 1998

40

Development of heart rate rhythmicity in Muscovy duck embryos

Joachim Höchel, Elmar Mohr, Martin Nichelmann, Ralph Pirow, Hiroshi Tazawa

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1999

Language:

english

File:

PDF, 306 KB

english, 1999

41

The role of convection in millimeter-sized animals — an optophysiological case study

R Pirow, RJ Paul

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1999

Language:

english

File:

PDF, 78 KB

english, 1999

42

The role of convection in millimeter-sized animals — an optophysiological case study

R Pirow, RJ Paul

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1999

Language:

english

File:

PDF, 136 KB

english, 1999

43

The development of novel targeted therapeutics for treatment of multiple myeloma research roundtable

Kenneth C. Anderson, Bart Barlogie, James R. Berenson, William S. Dalton, Julian Adams, Melissa Alsina, Pirow Bekker, Peter L. Bergsagel, Lawrence Boise, Kyle Chan, Asher A. Chanan-Khan, Raymond Comen

Journal:

European Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

44

A method for noninvasive, long-term recording of the avian embryo heart rate

Ralph Pirow, Rainer Bilsing, Martin Nichelmann, Joachim Höchel

Journal:

Physiology & Behavior

Year:

1995

Language:

english

File:

PDF, 370 KB

english, 1995

45

A randomized, double-blind comparison of risedronate and etidronate in the treatment of paget’s disease of bone

Paul D Miller, Jacques P Brown, Ethel S Siris, Mohammad S Hoseyni, Douglas W Axelrod, Pirow J Bekker

Journal:

The American Journal of Medicine

Year:

1999

Language:

english

File:

PDF, 122 KB

english, 1999

46

The process of hypoxic induction of Daphnia magna hemoglobin: subunit composition and functional properties

Bettina Zeis, Bertram Becher, Tobias Lamkemeyer, Silke Rolf, Ralph Pirow, Rüdiger Jörg Paul

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 689 KB

english, 2003

47

392 PROTECT-1 Study Demonstrated Efficacy of the Intestine-Specific Chemokine Receptor Antagonist CCX282-B (Traficet-EN) in Treatment of Patients with Moderate to Severe Crohn's Disease

Satish Keshav, Daniel Johnson, Pirow Bekker, Thomas J. Schall

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 123 KB

english, 2009

48

647 Chemokine Receptor Antagonist CCX282-B (Traficet-En™) Maintained Remission of Crohn's Disease in PROTECT-1 Study

Satish Keshav, Daniel Johnson, Thomas Schall, Pirow Bekker

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 76 KB

english, 2010

49

The hen's egg test for micronucleus-induction (HET-MN): Results of the method transfer prior a validation study

Reisinger, K., Fieblinger, D., Heppenheimer, A., Kreutz, J., Luch, A., Maul, K., Pirow, R., Poth, A., Strauch, P., Wolf, T.

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 79 KB

english, 2013

50

Tu1652 CCX507, an Orally Bioavailable Antagonist of the Chemokine Receptor CCR9, for the Treatment of IBD

Walters, Matthew, Ebsworth, Karen, Sullivan, Tim, Zhang, Penglie, Powers, Jay, Bekker, Pirow, Dairaghi, Daniel, Seitz, Lisa, Ertl, Linda, Jaen, Juan, Schall, Thomas

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 63 KB

english, 2013

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